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To discover new nematicidal succinate dehydrogenase (SDH) inhibitors with novel structures, we conducted a virtual screening of the ChemBridge library with 1.7 million compounds based on ligand‐pocket interactions. The homology model of Caenorhabditis elegans SDH was established, along with a pharmacophore model based on ligand‐pocket interactions. After the pharmacophore‐based and docking‐based screening,...