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The OpenBiomind toolkit is used to apply GA, GP and local search methods to analyze a large SNP dataset concerning late-onset Alzheimer's disease (LOAD). Classification models identifying LOAD with statistically significant accuracy are identified, and ensemble-based important features analysis is used to identify brain genes related to LOAD, most notably the solute carrier gene SLC6A15. Ensemble...
Traveling salesman problem (TSP) is one of the most difficult problems in the combinatorial optimization area. The goal of TSP is to find one path that can travel between all the nodes (instances) of the graph just once (Hamiltonian tour) in the smallest tour, that is, smallest Euclidian distance. In this context, many other meta-heuristics techniques based on evolutionary algorithms have been propose...
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