Search results for: Aihua Zhang

Items from 1 to 20 out of 271 results

article

Effect of adding lignin on preparation and properties of pitch/PAN‐derived electrospun nanofibers inducing cross‐linking structure

Jialing Zou, Mengzhu Li, Jiahui Zhang, Yong Qi, more

Journal of Applied Polymer Science > 141 > 35 > n/a - n/a

In this work, the content of lignin, pitch, and PAN as well as the preparation process would be systematically controlled in order to prepare carbon nanofibers (CNFs) with cross‐linked structure, high specific surface area, and good flexibility. The evolution of nanofibers with different lignin contents during stabilization and carbonization were explored, and the properties of the resultant CNFs...

article

How to Stabilize the Current of Efficient Inverted Flexible Perovskite Solar Cells at the Maximum Power Point

Xingjuan Ma, Wenli Peng, Shusen Jiang, Mingpo Li, more

Small > 20 > 26 > n/a - n/a

Inverted flexible perovskite cells (fPSCs) have attracted much attention for their high efficiency and power per weight. Still, the steady–state output is one of the critical factors for their commercialization. In this paper, it is found that the steady–state current of inverted fPSCs based on nickel oxide nanoparticles (n‐NiO_x) continuously decreases under light illumination. Conversely, those based...

article

Non‐invasive measurement of blood pressure waveform based on spatiotemporal multi‐dimensional pulse waves

Dongmei Lin, Hengkun Wang, Aihua Zhang, Jason Gu, more

International Journal of Imaging Systems and Technology > 34 > 2 > n/a - n/a

Continuous monitoring of blood pressure (BP) waveform is essential for the prevention and diagnosis of cardiovascular diseases because it contains rich information. A vision‐based non‐invasive measurement method of BP waveform was proposed in this work. A binocular vision pulse acquisition system was utilized to collect continuous pulse images in a predetermined area of radial artery, and multi‐dimensional...

article

The application of radiomics machine learning models based on multimodal MRI with different sequence combinations in predicting cervical lymph node metastasis in oral tongue squamous cell carcinoma patients

Sheng Liu, Aihua Zhang, Jianjun Xiong, Xingzhou Su, more

Head & Neck > 46 > 3 > 513 - 527

Background The purpose of this study was to explore preliminary the performance of radiomics machine learning models based on multimodal MRI to predict the risk of cervical lymph node metastasis (CLNM) for oral tongue squamous cell carcinoma (OTSCC) patients. Methods A total of 400 patients were enrolled in this study and divided into six groups according to the different combinations of MRI sequences...

article

Compound heterozygous variants in WLS gene causes Zaki syndrome

Cuicui Yu, Chunli Wang, Wei Zhou, Aihua Zhang, more

Clinical Genetics > 104 > 2 > 226 - 229

Biallelic Wnt ligand secretion mediator (WLS gene) variants are associated with Zaki syndrome (OMIM: #619648). Here, we report the first case with Zaki syndrome in the Chinese population. Whole‐exome gene sequencing (WES) identified compound heterozygous variants in the WLS gene (c.1427A > G; p.Tyr476Cys and c.415C > T, p.Arg139Cys; NM_001002292) in a 16‐year‐old boy presenting with facial dysmorphism,...

article

Public risk perceptions, emotions and behaviours under a major epidemic: A structural equation model analysis

Dandan Wang, Aihua Zhang, Xianqiong Feng

Journal of Advanced Nursing > 79 > 6 > 2280 - 2292

Aim To explore the relationships between public risk perceptions, emotions and behaviours during a major epidemic. Design Exploratory cross‐sectional design. Methods The 701 subjects were surveyed using self‐administered questionnaires, including the General Information Questionnaire, Public Risk Perceptions Questionnaire, Public Emotions Questionnaire and Public Behaviours Questionnaire. The...

article

The role of poly (ADP‐ribose) glycohydrolase in phosphatase and tensin homolog deficiency endometrial cancer

Yanyan Sun, Yi Shi, Hui Liu, Chunmei Lv, more

Journal of Obstetrics and Gynaecology Research > 49 > 4 > 1244 - 1254

Aim To explore the relationship between poly(ADP‐ribose) glycohydrolase (PARG) and the occurrence, development, and prognosis of endometrial carcinoma (EC), and investigate whether the PARG inhibitor PDD0017273 could increase the sensitivity of EC cells to cisplatin. Methods The expression of PARG, phosphatase and tensin homolog (PTEN), and p53 in normal endometrial tissues (NE), endometrial hyperplasia...

article

An ultra‐high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry identification and characterization of the active constituents from Abrus mollis Hance

Zhien Tan, Shimin Chen, Mengli Zhang, Xiaosheng Qu, more

Journal of Separation Science > 46 > 2 > n/a - n/a

Abrus mollis Hance is a traditional Chinese medicine that is widely used to treat acute and chronic hepatitis, steatosis, and fibrosis. Its therapeutic qualities of it have long been acknowledged, although the active ingredients responsible for its efficacy and the mechanisms of its action are unknown. In this study, the chemical constituents absorbed into the blood from Abrus mollis Hance were assessed...

article

The identification of a novel CCNQ gene tail extension variant contributing to syndactyly, telecanthus and anogenital and renal malformations syndrome

Ruochen Che, Chunli Wang, Songming Huang, Bixia Zheng, more

Clinical Genetics > 103 > 2 > 179 - 189

The “toe syndactyly, telecanthus and anogenital and renal malformations” (STAR) syndrome is a rare X‐linked dominant inherited kidney ciliopathy caused by CCNQ gene mutations. Here, we investigated the genotype and phenotype in the first two twin sisters with a novel tail extension CCNQ variant in Asia. Genetic variants of the pedigree were screened using whole‐exome sequence analysis and validated...

article

Rapid characterization of chemical constituents in Naoling Pian by LC‐MS combined with data processing techniques

Zhe Chen, Guangli Yan, Yu Yang, Hui Sun, more

Journal of Separation Science > 45 > 18 > 3431 - 3442

Naoling Pian is a prescription composed of 15 herbs, which is mainly used for the treatment of insomnia in clinical practice. However, the chemical constituents in Naoling Pian are numerous and unclear, which hinders the interpretation of its bioactive constituents and the subsequent research on the material basis for pharmacodynamics. The purpose of this study is to develop a rapid method for identifying...

article

Role of N6‐methyladenosine RNA modification in the imbalanced inflammatory homeostasis of arsenic‐induced skin lesions

Fan Yang, Aihua Zhang

Environmental Toxicology > 37 > 8 > 1831 - 1839

This study aimed to investigate the effect of N6‐methyladenosine (m⁶A) modification in modulating inflammatory homeostasis of arsenic (As)‐induced skin lesions. Our bioinformatic analysis revealed abnormal expression of m⁶A RNA methylation regulators and cytokines in the arsenic‐exposed population. In human keratinocytes, arsenite increased the levels of m⁶A methylation by upregulating the RNA methyltransferase...

article

Front Cover: Rapid characterization of the constituents in Jigucao capsule using ultra high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry

Taiping Li, Mengli Zhang, Zhien Tan, Jianhua Miao, more

Journal of Separation Science > 45 > 3 > NA - NA

DOI: 10.1002/jssc.202100664 The cover picture shows the qualitative analysis of Jigucao capsule (JGCC), a well‐known Chinese Patent Medicine for the treatment of acute and chronic hepatitis and cholecystitis. A rapid and robust method was established by high‐throughput ultra high performance liquid chromatography with quadrupole time of flight mass spectrometry. A total of 144 compounds in JGCC were...

article

Rapid characterization of the constituents in Jigucao capsule using ultra high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry

Taiping Li, Mengli Zhang, Zhien Tan, Jianhua Miao, more

Journal of Separation Science > 45 > 3 > 677 - 696

Jigucao capsule is a well‐known Chinese patent medicine for the treatment of acute and chronic hepatitis and cholecystitis. The chemical components of Jigucao capsule were not clear resulting from the paucity of relevant studies, which hindered the research of the pharmacological mechanism, the comprehensive development, and utilization of Jigucao capsule in clinical studies. By establishing a high‐throughput...

article

Sulphite‐corrected, non‐phenolic and phenolic antioxidant capacities of fruit wines profiled by differential Folin‐Ciocalteu assay

Aihua Zhang, Lingwen Zeng, Huijie Bo, William James Hardie

International Journal of Food Science & Technology > 57 > 2 > 1259 - 1272

The Folin‐Ciocalteu reagent (FCR) assay is a reliable and robust, in vitro measure of antioxidant capacity (AOC) of foods but in winemaking its use has generally been confined to measuring total phenolics. However, the contributions of non‐phenolics and sulphites, and total AOC are also of interest for winemaking process control and human health functionality. Accordingly, we adapted the FCR assay...

article

Imbalanced inflammatory response in subchronic arsenic‐induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell–cell interactions

Ling Dong, Yonglian Liu, Dapeng Wang, Kai Zhu, more

Environmental Toxicology > 36 > 10 > 2073 - 2092

Arsenic is a well‐known environmental toxicant and carcinogen, which has been epidemiologically proved related to the increased hepatic disorders. Researches have shown that aseptic inflammation and abnormal immune response are associated with arsenic‐induced liver injury. However, the immunotoxic effects of liver have not been extensively characterized. Ginkgo biloba extract (GBE), a natural products...

article

miR‐486‐3p regulates CyclinD1 and promotes fluoride‐induced osteoblast proliferation and activation

Ting Ouyang, Yu Qin, Keke Luo, Xue Han, more

Environmental Toxicology > 36 > 9 > 1817 - 1828

Fluoride is a persistent environmental pollutant, and its excessive intake contributes to skeletal and dental fluorosis. The mechanisms underlying fluoride‐induced abnormal osteoblast proliferation and activation, which are related to skeletal fluorosis, have not yet been fully clarified. As important epigenetic regulators, microRNAs (miRNAs) participate in bone metabolism. On the basis of our previous...

article

miR‐21‐regulated M2 polarization of macrophage is involved in arsenicosis‐induced hepatic fibrosis through the activation of hepatic stellate cells

Junchao Xue, Tian Xiao, Shaofeng Wei, Jing Sun, more

Journal of Cellular Physiology > 236 > 8 > 6025 - 6041

Arsenicosis induced by chronic exposure to arsenic is recognized as one of the main damaging effects on public health. Exposure to arsenic can cause hepatic fibrosis, but the molecular mechanisms by which this occurs are complex and elusive. It is not known if miRNAs are involved in arsenic‐induced liver fibrosis. We found that in the livers of mice exposed to arsenite, there were elevated levels...

article

Discharge teaching, readiness for hospital discharge and post‐discharge outcomes in cataract patients: A structural equation model analysis

Aihua Zhang, Xianqiong Feng, Chujin Qiu, Lopez Violeta

Journal of Nursing Management > 29 > 3 > 543 - 552

Aim To explore the interaction mechanism of cataract patients’ quality of discharge teaching, discharge readiness and post‐discharge outcomes using structural equation model analysis. Background The quality of discharge teaching and discharge readiness are two indicators used to evaluate the quality of hospital discharge services. Little research has been done on the quality of discharge teaching,...

article

Multi‐centre study of the clinical features and gene variant spectrum of Gitelman syndrome in Chinese children

Qian Shen, Jiemei Chen, Minghui Yu, Zhi Lin, more

Clinical Genetics > 99 > 4 > 558 - 564

Based on the Chinese Children Genetic Kidney Disease Database (CCGKDD), we established a pediatric Gitelman syndrome (GS) cohort to explore the phenotype and genotype characteristics. Thirty‐two patients with SLC12A3 gene variants were collected. Five cases (16%) were homozygous, 16 (50%) were compound heterozygous, 10 (31%) carried only a single variant, and the other one harbored two de novo variants...

article

GBE attenuates arsenite‐induced hepatotoxicity by regulating E2F1‐autophagy‐E2F7a pathway and restoring lysosomal activity

Xiong Chen, Dapeng Wang, Baofei Sun, Chunyan Liu, more

Journal of Cellular Physiology > 236 > 5 > 4050 - 4065

Arsenic is an environmental toxicant. Its overdose can cause liver damage. Autophagy has been reported to be involved in arsenite (iAs³⁺) cytotoxicity and plays a dual role in cell proliferation and cell death. However, the effect and molecular regulative mechanisms of iAs³⁺ on autophagy in hepatocytes remains largely unknown. Here, we found that iAs³⁺ exposure lead to hepatotoxicity by inducing autophagosome...

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INFONA - science communication portal

Search results for: Aihua Zhang

Effect of adding lignin on preparation and properties of pitch/PAN‐derived electrospun nanofibers inducing cross‐linking structure

How to Stabilize the Current of Efficient Inverted Flexible Perovskite Solar Cells at the Maximum Power Point

Non‐invasive measurement of blood pressure waveform based on spatiotemporal multi‐dimensional pulse waves

The application of radiomics machine learning models based on multimodal MRI with different sequence combinations in predicting cervical lymph node metastasis in oral tongue squamous cell carcinoma patients

Compound heterozygous variants in WLS gene causes Zaki syndrome

Public risk perceptions, emotions and behaviours under a major epidemic: A structural equation model analysis

The role of poly (ADP‐ribose) glycohydrolase in phosphatase and tensin homolog deficiency endometrial cancer

An ultra‐high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry identification and characterization of the active constituents from Abrus mollis Hance

The identification of a novel CCNQ gene tail extension variant contributing to syndactyly, telecanthus and anogenital and renal malformations syndrome

Rapid characterization of chemical constituents in Naoling Pian by LC‐MS combined with data processing techniques

Role of N6‐methyladenosine RNA modification in the imbalanced inflammatory homeostasis of arsenic‐induced skin lesions

Front Cover: Rapid characterization of the constituents in Jigucao capsule using ultra high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry

Rapid characterization of the constituents in Jigucao capsule using ultra high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry

Sulphite‐corrected, non‐phenolic and phenolic antioxidant capacities of fruit wines profiled by differential Folin‐Ciocalteu assay

Imbalanced inflammatory response in subchronic arsenic‐induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell–cell interactions

miR‐486‐3p regulates CyclinD1 and promotes fluoride‐induced osteoblast proliferation and activation

miR‐21‐regulated M2 polarization of macrophage is involved in arsenicosis‐induced hepatic fibrosis through the activation of hepatic stellate cells

Discharge teaching, readiness for hospital discharge and post‐discharge outcomes in cataract patients: A structural equation model analysis

Multi‐centre study of the clinical features and gene variant spectrum of Gitelman syndrome in Chinese children

GBE attenuates arsenite‐induced hepatotoxicity by regulating E2F1‐autophagy‐E2F7a pathway and restoring lysosomal activity

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