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NF-κB is a transcriptional regulator that plays a key role in immunity, inflammation and programmed cell death. We generated a PC12 cell line termed PC12κBluc that contains an integrated NF-κB-responsive reporter gene to directly measure NF-κB activity. The ''classical'' activators of NF-κB, phorbol 12-O-tetradecanoate-13-acetate and tumor necrosis factor α, strongly induced NF-κB activity in PC12κBluc...
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