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In the recent years the topic of irreversible electroporation has created an excitement in the ablation community due to its advantageous characteristics. In this chapter, we will explore these advantages such as complete cell death, demarcated ablation zones, quick procedure time, feasibility with real time imaging, and the lack of the “heat sink” effect that is affecting currently used ablation...
Head and neck cancers account for a small percent of new cancer cases each year in comparison to other cancers. However, the diagnosis of this disease is usually life threatening and negatively impacts the quality of the patient’s life. With various treatments or therapies available for the different stages of squamous cell carcinoma of the head and neck (SCCHN), the most prominent type of head and...
Electroporation refers to the ability of electric fields to cause the formation of reversible or irreversible pores in the membranes of cells. Reversible electroporation (RE) is now in widespread use as a method of delivering chemicals and large molecules to cells, both as a research tool and a clinical technique. Recently, irreversible electroporation (IRE) has garnered interest as a stand-alone...
Image-guided ablation has evolved rapidly in the past decade into a competitive technique for treating focal solid malignancies. However, as they rely mainly on thermal energy, such as radiofrequency or microwave, many tumors close to sensitive organs, such as ducts, bowel, and nerves, still remain nonablatable owing to the risk of thermal injury. Irreversible electroporation is a novel ablation modality...
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