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Background and AimSeveral epidemiological studies have shown that coffee intake attenuates the progression of liver fibrosis; however, the mechanism is unclear.
AimsWe investigated the direct effects of caffeine on hepatic stellate cells (HSCs) and assessed whether caffeine attenuated intrahepatic fibrosis in rat model of liver cirrhosis.
MethodsHuman hepatic stellate cell line, an immortalized...
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