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Background
Minimal residual disease (MRD) is an important prognostic factor for survival in adults with acute leukemia. The role of pretransplantation MRD status in myelodysplastic syndrome with excess blasts (MDS‐EB) is unknown. This study retrospectively analyzed the relationship between pretransplantation MRD status and long‐term survival.
Materials and Methods
Patients with MDS‐EB who underwent...
BACKGROUNDTo understand the mechanism of frequent and early lymph node metastasis in high‐risk human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma (OPSCC), this study investigated whether β‐catenin is regulated by the HPV oncoprotein and contributes to OPSCC metastasis.
METHODSExpression levels of p16, β‐catenin, and epidermal growth factor receptor (EGFR) were examined in...
BACKGROUND:Distinct morphologic features of microvascular endothelium exist in tumor tissues. The objective of this study was to investigate the prognostic value of endothelium‐coated tumor clusters (ECTCs) in hepatocellular carcinoma (HCC).
METHODS:ECTCs were evaluated by immunohistochemical staining for cluster of differentiation 34 (CD34) (a cell surface glycoprotein which is expressed specifically...
BACKGROUND:Although recent genome‐wide association studies have been conducted to reveal the relation between variations in the α5 nicotinic receptor subunit and lung cancer in European and American populations, to the authors' knowledge, no definite information on the role of nicotine acetylcholine receptor subunit α5 (CHRNA5) in lung cancer risk has been obtained in a Chinese population.
METHODS:To...
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