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AbstractWe cloned the 5 upstream region of IL-15 genomic DNA and examined promoter activity in macrophages stimulated with lipopolysaccharide(LPS). The 1.2 kilobase (kb) fragment of the 5 upstream region contained binding elements for LPS-inducible transcription factors such as NFIL-6 or NF-B. Determined by luciferase assay following transient transfection in the J774A.1 macrophage cell line, the...
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