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Tetanus Toxin (TeTx), a potent neurotoxin, inhibits the release of neurotransmitters. It is composed of two polypeptidic chains linked together by a disulphide bond. The heavy chain H controls the fixation of TeTx on cell surface as well as the internalization and the translocation of the light chain L into the cytoplasm. The L chain is responsible for the clivage of synaptobrevin, a protein of...
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