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Abstract. Antagonistic effects of the novel suramin analogue 4,4,4,4-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid (NF449) were studied on contractions of the rat vas deferens elicited by ,-methylene ATP (meATP; mediated by P2X1 receptors), contractions of the guinea-pig ileal longitudinal smooth muscle elicited by meATP (mediated by P2X3 receptors)...
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