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Dehydration of serine/threonine residues necessitates the activity of a dehydratase enzyme (domain) during the biosynthesis of RiPP. Recently, it was reported that dehydration in the thioviridamide pathway relies on a distinct dehydratase complex that showcases the activities of a phosphotransferase TvaC for serine/threonine phosphorylation and a lyase TvaD for subsequent phosphate elimination. Herein,...
In the presence of a template molecule, roxithromycin (RM), novel molecularly imprinted polymer (MIP) microspheres were prepared by one-step precipitation polymerization using methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA) and 2'2-azobisisobutyronitrile (AIBN) as functional monomer, cross-linker and initiator, respectively. The scanning electron microscopy exhibited that the imprinted...
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