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Introduction Heat shock protein 90 (HSP90) is a key component of a multichaperone complex involved in the post-translational folding of a large number of client proteins, many of which play essential roles in tumorigenesis. HSP90 has emerged in recent years as a promising new target for anticancer therapies. Methods The concentrations of the HSP90 inhibitor NVP-AUY922 required to reduce cell numbers...
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