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Histamine H 3 receptors (H 3 Rs) co-localize with dopamine (DA) D 1 receptors (D 1 Rs) on striatal medium spiny neurons and functionally antagonize D 1 R-mediated responses. The intra-striatal administration of D 1 R agonists reduces DA release whereas D 1 R antagonists have the opposite effect. In this work, a microdialysis method was used to...
Functional impairment after brain injury (BI) has been attributed to the inhibition of regions that are related to the injured site. Therefore, noradrenaline (NA) is thought to play a critical role in recovery from motor injury. However, the mechanism of this recovery process has not been completely elucidated. Moreover, the locus coeruleus (LC) projects from the pons through the rat sensorimotor...
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