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ω-3 PUFA contains neurotrophic actions, which are associated with its antidepressant properties. In this study, we found that lipopolysaccharide (LPS) exposure induced the rats to a depression-like state and caused disturbances in neurotrophic network, which were partly restored by ω-3 PUFA pretreatment. Given the well-documented role of BDNF in depression, we further assessed the expression of precursor...
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