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The slide‐free, stain‐free multimodal multiphoton imaging provides rich morphological and chemical information about the tissue. Non‐destructive and automated qualitative and quantitative assessment of the pathological changes provides promising potentials for building a more standardizable system for the evaluation of the response to neoadjuvant therapy in rectal cancer.
Further details can be found...
Neoadjuvant therapy has become a standard treatment for patients with locally advanced rectal cancer to achieve better prognostic outcomes. The response to treatment has been shown to correlate closely with the prognosis. However, current evaluation systems only provide coarse assessment on limited information, due to the lack of accurate and reproducible approach for quantitation of different types...
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