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Rationale Antipsychotic-induced extrapyramidal side effects (EPS) are still a major problem in the treatment of schizophrenia. Serotonin 2C receptors (5-HT2C) have regulatory effects on dopaminergic pathways in brain regions involved with EPS. Polymorphisms in the 5-HT2C gene (HTR2C) have been suggested to be associated with the risk of developing EPS. Objective Our purpose was to evaluate the impact...
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