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The XylS protein is the positive transcription regulator of the TOL plasmid meta-cleavage pathway operon Pm. XylS belongs to the AraC family of transcriptional regulators and exhibits an N-terminal domain involved in effector recognition, and a C-terminal domain, made up of seven α-helices conforming two helix–turn–helix DNA-binding domains. α-Helix 3 and α-helix 6 are the recognition helices. In...
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