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BACKGROUND
Active surveillance (AS) for prostate cancer includes follow‐up with serial prostate biopsies. The optimal biopsy frequency during follow‐up has not been determined. The goal of this investigation was to use longitudinal AS biopsy data to assess whether the frequency of biopsy could be reduced without substantially prolonging the time to the detection of disease with a Gleason score ≥...
BACKGROUNDIn men with clinically localized prostate cancer who have undergone at least 1 previous negative biopsy and have elevated serum prostate‐specific antigen (PSA) levels, long‐term health outcomes associated with the assessment of urinary prostate cancer antigen 3 (PCA3) and the transmembrane protease, serine 2 (TMPRSS2):v‐ets erythroblastosis virus E26 oncogene homolog (avian) (ERG) gene fusion...
BACKGROUND
Integrating quality‐of‐life (QOL) outcomes into clinics may assist providers in identifying and responding to problems experienced by cancer survivors. To date, however, patient‐reported outcomes (PROs) such as QOL are used infrequently to guide care. We integrated QOL assessments into a prostate cancer survivorship clinic and compared recovery and satisfaction among men managed in the...
BACKGROUND:Limited survival benefit and excess treatment because of prostate‐specific antigen (PSA) screening in randomized trials suggests a need for more restricted selection of prostate biopsy candidates by discerning risk of histologically aggressive versus indolent cancer before biopsy.
METHODS:Subjects undergoing first prostate biopsy enrolled in a multicenter, prospective cohort of the National...
BACKGROUND:Because there is limited population‐based evidence supporting the comparative effectiveness of laparoscopic radical nephrectomy (LRN) after its widespread adoption, we compared trends in hospital‐based outcomes among patients with kidney cancer treated with LRN or open radical nephrectomy (ORN).
METHODS:Using linked SEER‐Medicare data, the authors identified patients with kidney cancer...
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