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We studied circulating levels of endothelin-1, catecholamines and nitric oxide after a mental arithmetic test in 14 patients with early ischemic lesions of the extremities due to systemic sclerosis and slightly impaired peripheral vascular flow. The test induced an increase (P<0.01) in blood pressure, heart rate, endothelin-1 and catecholamine levels, whereas it did not change the low basal levels...
Twelve patients with chronic critical limb ischemia in whom a spinal cord stimulation (SCS) system had been implanted for at least one year had increased microvascular flow and achieved healing of trophic acral lesions. After switching off the system, the clinical improvement persisted for 10 days and the neurohormonal pattern showed high plasma values of β-endorphin and Met-enkephalin, normal dynorphin...
After hyperventilation, systolic blood pressure (SBP) significantly decreased in 10 subjects (group 1), did not change in eight (group 2) and increased in 15 (group 3). Diastolic blood pressure and heart rate increased in all groups. The decrease in SBP was associated with a decrease in plasma catecholamines and increase in β-endorphin, whereas the increase in SBP was accompanied by an increase in...
Fontana, F., P. Bernardi, E. Merlo Pich, S. Boschi, R. De Iasio and S. Spampinato. Endogenous opioid peptides and mental stress in congestive heart failure patients. Peptides 19(1) 21-26, 1998.-Two groups of patients with acute congestive heart failure (CHF), New York Heart Association class III, presenting elevated plasma values of β-endorphin, norepinephrine, atrial natriuretic factor (ANF) and...
Fontana, F., P. Bernardi, E. Merlo Pich, S. Boschi, R. De Iasio, S. Spampinato and G. Grossi. Opioid peptide modulation of circulatory and endocrine response to mental stress in humans. Peptides 18(2) 169–175, 1997.—Healthy subjects were classified according to their percent increase in systolic blood pressure (SBP) after mental arithmetic test (MAT) as low (ΔSBP 9.3–15.1%, n = 15) and high (ΔSBP...
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