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Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy causing progressive vision loss. Ocular redox status is altered in RP suggesting oxidative stress could contribute to their progression. In addition, it is accompanied by chronic and sustained inflammation, including M1 microglia activation. In our group we evaluated,...
Aim
To assess and compare the microbiome of paired root apices and periapical lesions from cases with failed endodontic treatment and to associate the microbiome and bacterial metabolic pathways in both sites with asymptomatic apical periodontitis (AAP) and symptomatic apical periodontitis (SAP), using next‐generation sequencing (NGS).
Methodology
Matched root apices and periapical lesions of patients...