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Isolated spinal cord preparations from Rana Ridibunda frogs were used for studies of the effects of the GABAB receptor agonists (–)-baclofen (50 and 100 μM) and GABA (4–8 mM) and the specific GABAB receptor antagonist 2-hydroxysaclofen (100 μM) on the transmission of signals from fibers of the ventral columns monosynaptically connected with motoneurons in segments 9 and 10. These experiments showed...
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