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TP53 mutation is the most frequent molecular event in BRCA1-associated ovarian carcinomas. TP53 status may be a confounding factor in the evaluation of clinical importance of other proteins. We aimed to evaluate the clinical significance of BRCA1 mutations with respect to the TP53 accumulation status in 159 high-grade ovarian carcinomas.Statistical analyses were done with the Kaplan-Meier method,...
Background. Massive bleeding from an exophytic tumor is a serious complication in advanced cases of cervical carcinoma. With persistent bleeding the embolization or ligation of an artery is required.Case. This report describes the technique of laparoscopic ligation of the hypogastric artery in patients with massive bleeding in advanced cases of cervical cancer (FIGO Stage III). Laparoscopy was performed...
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