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A breast cancer risk assessment based on fuzzy set theory and fuzzy logic is proposed in this paper. The proposed fuzzy breast cancer system maps two controlled and two non-controlled input variables into the risk of breast cancer occurrence. Such an approach covers the age, menopause, simplified fuzzy body mass index (FBMI), and the existence of hormone replacement as input linguistic variable. The...
AMP-activated protein kinase (AMPK) is a metabolite- sensed protein kinase in various eukaryotes. The activated AMPK regulates important proteins which cause diabetes, obesity, metabolic aberrant, and also breast cancer. In this study, the yeast AMPK structure was used as a template to model the human AMPK structure. By homology modeling, the reliable AMPK structure was built, and the active binding...
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