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Evolution through natural selection can be described as driven by a perpetual conflict of individuals competing for limited resources. Recently, I postulated that the shortage of resources godfathered the evolutionary achievements of the differentiation-apoptosis programming [Rev. Neurosci. 12 (2001) 217]. Unicellular deprivation-induced differentiation into germ cell-like spores can be regarded as...
Human mitochondrial DNA, the 25th chromosome, is a 16 569 base pair long circular molecule, that encoders a variety of genes for the translational machinery of the mitochondrion, as well as 13 structural proteins, that are all subunits of the respiratory chain (RC). A variety of alterations of mitochondrial DNA (mtDNA) are now functionally and genetically linked to human disease, including encephalomyopathies,...
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