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Minor groove aligned tetrads resulting from the association of Watson–Crick base pairs stabilize a distinct class of four-stranded DNA structures, different from G-quadruplexes or i-motifs. These tetrads can be formed by several arrangements of G–C or A–T base pairs. Here we prove that minor groove tetrads can be also formed by G–T mismatches. In this manuscript we describe the dimeric solution structures...
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