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In vivo monitoring of the hypoxic area is urgently required. Near infrared (NIR) fluorescence-active fluorophores with excellent photo stability are preferable for in vivo imaging. A novel rational designed turn-on fluorescent probe with high selectivity and long-wavelength was synthesized which was applied in bioreductase (cytochrome P450 reductase which overexpressed in tumor cells) and hypoxia...
Detection of live cells has been difficult with conventional biochemical techniques that require the lysis of cells to release a biomarker. This study describes the simple construction of a galactosyl anthraquinone dye for the label-free impedance detection of live cancer cells. A click dipolar reaction of an alkynyl anthraquinone with azido galactoside yields the anthraquinone probe which can be...
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