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The mechanics of blood flow with clot formation, growth, and dissolution is affected by the biochemical reactions underlying clot formation, growth, and dissolution. A framework of models combining the biochemistry and mechanics of the phenomenon should include a model for the biochemistry underlying the same. A mathematical model to describe the biochemical changes underlying the formation, growth...
A mathematical model comprised of 23 reaction–diffusion equations is used to simulate the biochemical changes and transport of various reactants involved in coagulation and fibrinolysis in quiescent plasma. The growth and lysis of a thrombus, as portrayed by the model equations, is governed by boundary conditions that include the surface concentration of TF–VIIa, the generation of XIa by contact activation...
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