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A novel hundred-microsecond histotripsy treatment method is proposed. This method utilizes the confocal dual-frequency of second harmonic superimposition control approach. A custom-designed transducer consisting of two confocal spherical-annular element arrays is used. The frequencies of the transducer are 1.1 and 2.2 MHz, and the peak negative pressures are 5 MPa and 12 MPa with shock wave. Due to...
Kidney cancer is a severe disease which can be treated by using a non-invasive, controllable and focused ultrasound surgery method-histotripsy. Previously, histotripsy produced by hundred-microsecond-long focused ultrasound pulses has been proposed by us, which generates mechanical homogenized lesion by employing boiling bubbles and high duty cycle compared with conventional methods. However, the...
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