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Previous study has demonstrated that pulsed HIFU with tens of microseconds pulse duration (PD) and 10kHz PRF is effective for cavitation generation. Meanwhile, with the assistance of PFC nanodroplets, cavitation can be further enhanced. Despite of higher efficiency, we also need cavitation to be precisely controlled and confined for sake of therapeutic safety, especially during the implementation...
Histotripsy is a new non-invasive therapy modality and can mechanically disintegrating target tissue for tumor treatment. In this study, we propose a strategy of dual frequency of fundamental and harmonic superimposition combined with hundred-microsecond-length pulses and two stages to get good use of the nonlinear regimes of enhanced cavitation and boiling. Confocal fundamental and harmonic superimposition...
This study aims at a sound field calculation for the spherical-section phased array and an optimization algorithm for the focus patterns of phased array ultrasound surgery. An efficient field calculation formula represented as an explicit expression is derived by the strategies of projection and binomial expansion. An optimization algorithm based on genetic algorithm is constructed by the suitable...
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