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This paper reported a microfluidic platform which realized the characterization of inherent single‐cell biomechanical and bioelectrical parameters simultaneously. Individual cells traveled through a constriction channel with deformation images and impedance variations captured and processed into cortical tension Tc, specific membrane capacitance Csm, and cytoplasmic conductivity σcy based on an equivalent...
As label‐free biomarkers, electrical properties of single cells have been widely used for cell‐type classification and cell‐status evaluation. However, as intrinsic bioelectrical markers, previously reported membrane capacitance and cytoplasmic resistance (e.g., specific membrane capacitance Cspecific membrane and cytoplasmic conductivity σcytoplasm) of tumor subtypes were derived from tens of single...
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