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Background
Neurogenic erectile dysfunction (NED) caused by cavernous nerve (CN) injury is a typical complication after pelvic surgery, which lacks efficient treatments. Acetyl‐L‐carnitine (ALCAR) has been proven to promote nerve repair.
Objectives
To investigate the effect and potential mechanism of ALCAR in the treatment of NED.
Materials and methods
Thirty‐two rats were randomly divided into...
Background
The population with diabetes mellitus‐induced erectile dysfunction is increasing rapidly, but current drugs are not effective in treating erectile dysfunction. Studies of the traditional Chinese medicine extract berberine on diabetes and its complications provide us with new ideas.
Objectives
To evaluate the therapeutic effect and potential mechanism of berberine on the erectile function...
Background
Janus kinase 2 (JAK2) is activated in diabetic mellitus (DM) conditions and may enhance oxidative stress, apoptosis and fibrosis in many tissues. Whether JAK2 activation is involved in the occurrence of diabetic erectile dysfunction (ED) is unknown.
Objectives
We performed this study to investigate the effect of JAK2 deficiency on diabetic ED.
Materials and methods
Conditional JAK2...