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Various pathological conditions contribute to pH fluctuations and affect the functions of vital organs such as the heart. In this study, we show that in rat cardiomyocytes, acidic extracellular pH (pHe) inhibits autophagy, whereas alkaline pHe stimulates it. We also find that adenosine monophosphate‐activated protein kinase (AMPK), mammalian target of rapamycin (mTOR) and Unc‐51‐like kinase 1 (ULK1)...
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