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Background.Ent‐11‐hydroxy‐15‐oxo‐kaur‐16‐en‐19‐oic acid (5F) is known to exhibit antitumor activity, but its mechanism is not completely understood. 5F has not been tested in laryngeal cancer.
Methods.Two laryngeal cancer cell lines were treated with 5F. Cell death was analyzed by MTT [3‐(4,5‐dimethylthiozol‐2‐yl)‐2,5‐diphenyltetrazolium bromide] and Annexin V assay. Nuclear factor kappa beta (NF‐κB)–...
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