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Early secretory antigen target 6 (ESAT‐6) is a dominant target for cell‐mediated immunity in the early phase of tuberculosis (TB) in patients with TB, causing T‐cell proliferation and gamma interferon (IFN‐γ) production, which has been considered to be a protective antigen that can be used for future vaccine development. Ag85A is the most essential component for bacterial survival within macrophages...
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