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Alkaline phosphatase (ALP) is an essential enzyme in various tissues, which has been reported to be extensively involved in various physiological and pathological processes. Fluorescent probe assays carried out in vivo are desirable for monitoring the ALP activity. In this study, a novel red-light fluorescent DHP probe, which exhibited good selectivity and high sensitivity, for monitoring the ALP...
A reversible off-on-type probe for pH sensing with fluorescence and surface-enhanced Raman scattering (SERS) dual-signal output, Rhodamine–phenanthroline (RGP), was designed and synthesized from Rhodamine 6G and 1,10-phenanthroline. Due to the molecular structure transformation between spirocyclic and ring-open forms, RGP exhibits varying fluorescence and SERS activities at different pH levels. The...
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