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The goal of this work is to examine the effects of pulse-inversion (PI) technique in combination with dual-frequency (DF) excitation method to separate the high-order nonlinear responses from microbubble contrast agents for improvement of image contrast. DF excitation method has been previously developed to induce the low-frequency ultrasound nonlinear responses from bubbles by using the composition...
The goal of this work was to test experimentally that exposing air bubbles or ultrasound contrast agents in water to amplitude modulated wave allows control of inertial cavitation affected volume and hence could limit the undesirable bioeffects.Focused transducer operating at the center frequency of 10MHz and having about 65% fractional bandwidth was excited by 3μs 8.5 and 11.5MHz tone-bursts to produce...
Detection of ultrasound contrast agents (UCAs) based on their nonlinear characteristics are popular for imaging blood perfusion. For microcirculation imaging, a higher frequency system (>10 MHz) is required to obtain higher spatial resolution. However, high-frequency nonlinear techniques usually suffer from insufficient signal-to-noise ratio (SNR) due to the intense attenuation and the limited...
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