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Microstructural and physiological changes are intense in the developing brain, thus considerably modifying parameters quantified by MRI (relaxation times, anisotropy and diffusivities). The latest advances in EPI enabled to non-invasively measure these parameters in infants in a reasonable acquisition time to follow brain maturation. To take advantage of the parameters complementarity, we first proposed...
Studying how the healthy human brain develops is important to understand early pathological mechanisms and to assess the influence of fetal or perinatal events on later life. Brain development relies on complex and intermingled mechanisms especially during gestation and first post-natal months, with intense interactions between genetic, epigenetic and environmental factors. Although the baby’s brain...
The human infant is particularly immature at birth and brain maturation, with the myelination of white matter fibers, is protracted until adulthood. Diffusion tensor imaging offers the possibility to describe non invasively the fascicles spatial organization at an early stage and to follow the cerebral maturation with quantitative parameters that might be correlated with behavioral development. Here,...
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