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Objective: Develop and evaluate a model of persistent atrial fibrillation (AF) and severe congestive heart failure (CHF). Methods: A single-chamber atrial pacemaker was implanted in pigs (20-30 kg). Burst atrial pacing at 42 Hz led to development of persistent AF. Immediately and 20 days after activation of the burst pacing protocol, animals underwent echocardiography. Heart rate, rhythm and general...
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