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The loss of function of exocyst subunit EXO70B1 leads to autoimmunity, which is dependent on TIR‐NBS2 (TN2), a truncated intracellular nucleotide‐binding and leucine‐rich repeat receptor (NLR). However, how TN2 triggers plant immunity and whether typical NLRs are required in TN2‐activated resistance remain unclear. Through the CRISPR/Cas9 gene editing system and knockout analysis, we found that the...
Nucleotide‐binding site (NBS)–leucine‐rich repeat (LRR) domain receptor (NLR) proteins play important roles in plant innate immunity by recognizing pathogen effectors. The Toll/interleukin‐1 receptor (TIR)‐NBS (TN) proteins belong to a subtype of the atypical NLRs, but their function in plant immunity is poorly understood. The well‐characterized Arabidopsis thaliana typical coiled‐coil (CC)‐NBS‐LRR...
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