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We succeeded in dispensing micro-droplet by a disposable on-chip inkjet mechanism. Novelty of this paper is summarized as follows. (1) We employed a glass plate bonded Poly-dimethylsiloxane (PDMS) membrane to obtain leaf spring structure whose spring coefficient is 14 times of the conventional PDMS membrane. As a result, we succeeded in dispensing droplets continuously (up to 10 Hz) by vibrating the...
Optical adhesion control of a functional gel microtool, made of hydrophilic photo-crosslinkable resin, was developed for on-chip cell manipulation. The functional gel microtool used can be manipulated by optical tweezers and functionalized by spiropyran chromospheres, which is a photochromic polymer. Spiropyran chromospheres were used for temporal cell adhesion of the gel microtool. The adhesiveness...
Nanomanipulation of a single influenza virus in a microfluidic chip for biomedical innovation was developed. We employed Robot on a Chip (RoC) to achieve stable manipulation of nano-scale biomaterials such as virus (size is about 100 nm). The microfluidic chip has independent virus chamber and cell chamber to make quantitative analysis such as single virus infection to a specific cell. Gel-microtool...
The track pitch of magnetooptical disks with metal guiding layers was reduced to less than the laser spot size by suppressing crosstalk. The recorded domain width was effectively confined by the width of the spiral-shape recording region from which the guiding layer was removed. The CNR was improved by using a substrate/enhancing layer/guiding layer/interference layer/recording layer structure. The...
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