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A direct controlled cell assembling technique based on rapid prototyping technology was developed in our laboratory to fabricate pre-defined three-dimensional tissue-engineered construct with interconnected porosity and multi-cells. Based on this technique, a cell controlled assembler II has been developed in which cell/hydrogel was deposited layer-by-layer with a pressure-controlled syringe. It could...
Advances in fabrication technologies have kept in bringing new directions to the field of tissue engineering. Recently, using Rapid Prototyping-based methods and hydrogel chemistries and cells, researchers have been able to assemble tissue engineering active organoids with complex 3-D architectures in vitro. Through analyzing the natural tissue structure and microenvironments, a bio-hierarchy structure...
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