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Background
Baicalin can attenuate myocardial ischemia‐reperfusion (I/R) on damage. However, the mechanisms are still not fully understood. The study aimed to investigate the antiapoptosis and anti‐inflammatory effects of baicalin on myocardial I/R‐induced injury.
Methods
We established male rats I/R model, and baicalin was intragastric administration after ischemia onset. All experimental animals...
The suppressor of cytokine signaling 3 (SOCS3) is an established negative feedback regulation transcription factor associated with leptin, tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ) and growth hormone (GH). However, the regulatory mechanism of SOCS3 on inflammation and apoptosis of adipocyte is still not clear. In this study, we found an increased expression of adipocyte inflammatory cytokines...
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