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This work focuses on the problematic of modeling the drug diffusion process that occurs in the human body when an anesthetic drug is taken up. This is performed here using emerging tools from fractional calculus, i.e. by using fractional-order impedance models (FOIMs). A novel interpretation is given to the classical pharmacokinetic and pharmacodynamic models for drug uptake in the body. The major...
This research focuses on modeling the diffusion process that occurs in the human body when an analgesic drug is taken up, by using fractional-order impedance models (FOIMs). We discuss the measurement of a suitable feedback signal that can be used in a model-based control strategy. With this knowledge an early dawn concept of a pain sensor is presented. The major challenges that are encountered during...
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