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Background
HS‐10234 is a novel prodrug of tenofovir developed to increase anti‐viral potency and to reduce systemic toxicities.
Aims
To evaluate the tolerability, pharmacokinetics and anti‐viral efficacy of HS‐10234 in patients with chronic hepatitis B (CHB) infection
Methods
Treatment‐naïve subjects with non‐cirrhotic CHB were divided into three groups (n = 12/group) and randomised within each...
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