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In the brain, NLRP3 (Nucleotide‐binding oligomerization domain, leucine‐rich repeat, and pyrin‐domain‐containing 3) inflammasome is mainly expressed in microglia located in the hippocampus and other mood‐regulated regions, which are particularly susceptible to stress. The activation of NLRP3 inflammasome and production of the activation products may contribute to the development of depressive disorder...
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