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In an attempt to develop an edible vaccine, we transformed a recombinant hepatitisBvirus (HBV) gene encoding the middle protein of HBV that contains the surface S and preS2antigen into potato by Agrobacterium-mediated transformation. The HBV gene was under control of either the CaMV35S promoter, the double35S promoter with the AlMV 5non-translated leader sequence, or the tuber-specific patatin promoter...
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