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Nowadays, spontaneous reporting systems (SRS) have been widely established to collect adverse drug events for ADR detection and analysis, e.g., the FDA Adverse Event Reporting System (FAERS). The SRS data are provided to the researchers, even open to the public, to foster the research of ADR detection and analysis. Normally, SRS data contains personal information and some sensitive value such as indication...
Spontaneous reporting systems of adverse drug events have been widely established in many countries to collect as could as possible all adverse drug events to facilitate the detection of suspected ADR signals via some statistical or data mining methods. Unfortunately, due to privacy concern or other reasons, the reporters sometimes may omit consciously some attributes, causing many missing values...
Nowadays, many countries have established spontaneous reporting systems (SRSs) to facilitate postmarketing surveillance of listed drugs and collect enough data for detecting unknown adverse drug reactions. Due to data in SRSs coming from different sources of reporters, there heralds the problem of duplicate reporting; even a small amount of duplicate records would bias the detection results. Although...
In this paper, we present the problem of and research issues for anonymizing spontaneous ADE reporting data for privacy-preserving ADR signal detection. Three main characteristics of spontaneous ADE data are identified, including rare ADE events, multiple individual records, and no sensitive attribute but having quasi-sensitive attributes. We examine the feasibility of contemporary privacy-preserving...
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