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Esophageal cancer (EC) is a prevalent malignancy associated with therapeutic resistance and poor prognosis. This study investigates the role of programmed death‐ligand 1 (PD‐L1) in esophageal cancer stem cell (ECSC) formation. ECSCs were enriched and characterized using various assays. We found that both PD‐L1 and bromodomain‐containing protein 4 (BRD4) were upregulated in ECSCs, promoting their stemness...
The roles of long noncoding RNA (lncRNA) MCF2L‐AS1 have been identified in colorectal cancer, however, its roles in lung cancer progression have never been revealed. Here, we found that lncRNA MCF2L‐AS1 was highly expressed in lung cancer tissues and cells, especially in non‐small cell lung cancer (NSCLC). Functional experiments showed that MCF2L‐AS1 knockdown suppressed the cancer stem cell (CSC)‐like...
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