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A major problem when analyzing bionanoparticles such as influenza viruses (approximately 100 nm in size) is the low sample concentrations. We developed a method for manipulating a single virus that employs optical tweezers in conjunction with dielectrophoretic (DEP) concentration of viruses on a microfluidic chip. A polydimethylsiloxane microfluidic chip can be used to stably manipulate a virus. The...
We proposed size-dependent microparticle filtration and particle trap by centrifugal force and mechanical restriction using three-dimensional magnetically driven microtool (3D-MMT) in a microfluidic chip. Novelties of this paper are summarized as follows. (1) Filtration of particles is robust against pressure fluctuation in microchannels rather than using only hydrodynamic force because particles...
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