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START aimed to compare angiographic outcome and chronic vessel response assessed by IVUS between primary stenting and optimal directional coronary atherectomy (DCA). One hundred twenty-two lesions suitable for either stenting (Palmaz-Schatz) or DCA were randomly assigned to a stent group (62 lesions) or a DCA group (60 lesions). Single or multiple Palmaz-Schatz stents were implanted with high pressure...
Background: The REstenosis ReDUction by Cutting Balloon Evaluation (REDUCE) is a prospective multicenter (44 Japaneses sites) registry to assess the efficacy of Cutting Balloon (CB).Methods: Total target registry is 800 patients, who are randomly assigned to either CB or conventional balloon angioplasty (POBA). At present, preliminary acute results are available for 208 patients out of a 460 patient...
Background: The optimal modality for stent restenosis remains unestablished. Cutting balloon angioplasty (CBA) is a strategy to reduce tissue injury and vessel stretch.Method: To clarify the efficacy and long-term outcomes of CBA for stent restenosis, we analyzed 167 lesions treated by CBA from 9 centers. Until August 1997, clinical and angiographic follow-up has completed in 80% and 72%, respectively...
We previously reported that cilostazol, a new synthetic platelet-aggregation inhibitor, inhibits intimal proliferation following directional coronary atherectomy and that it also significantly reduces restenosis following balloon angioplasty. The aim of this study was to determine the effect of cilostazol on neointimal proliferation following Palmaz-Schatz (P-S) stent implantation. Twenty nine lesions...
It is well known that Stenting decreases restenosis ratio after PTCA. On the other hand, recent papers reported that Stent implantation caused more increase in plaque area (PA) than other devices. To clarify the influence of stent implantation on PA increase, we attempted to compare PA change after intervention between stent and DCA in randomized trial. In this randomized trial (START) 115 lesions...
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